Early Transcriptional Responses of HepG 2 - A 16 Liver Cells to Infection by Plasmodium falciparum Sporozoites * [ i ]
نویسنده
چکیده
Received for publication, March 17,2011, and in revised form, June 1, 2011 Published,JBC Papers in Press, June 7, 2011, DOI10.1074/jbc.M111.240879 Rana Chattopadhyay*\ Patricia de Ia Vegac~.§, Sun H. Paik~, Yoko Murata\ Earl W. Ferguson~, Thomas L. Richie*11, and Guck T. Ooi From the* Malaria Program, United States Military Malaria Vaccine Program, §Walter Reed Army Institute of Research and the IINaval Medical Research Center, Silver Spring, Maryland 20910-7500 and'11Sun BioMedical Technologies Inc., Ridgecrest, California 93555
منابع مشابه
Early transcriptional responses of HepG2-A16 liver cells to infection by Plasmodium falciparum sporozoites.
Invasion of hepatocytes by Plasmodium sporozoites deposited by Anopheles mosquitoes, and their subsequent transformation into infective merozoites is an obligatory step in the initiation of malaria. Interactions between the sporozoites and hepatocytes lead to a distinct, complex and coordinated cellular and systemic host response. Little is known about host liver cell response to sporozoite inv...
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